{"id":2305,"date":"2022-01-26T12:05:06","date_gmt":"2022-01-26T12:05:06","guid":{"rendered":"https:\/\/ptnmr.web.ua.pt\/wp\/?page_id=2305"},"modified":"2022-02-13T18:22:32","modified_gmt":"2022-02-13T18:22:32","slug":"universidade-de-lisboa-ff","status":"publish","type":"page","link":"https:\/\/ptnmr.web.ua.pt\/index.php\/universidade-de-lisboa-ff\/","title":{"rendered":"Universidade de Lisboa – FF"},"content":{"rendered":"

 <\/p>\n\n\n\n\n
\"\"<\/td>\n\n
Faculdade de Farm\u00e1cia<\/div>\n
Universidade de Lisboa<\/div>\n
Avenida Professor Gama Pinto<\/div>\n
1649-003 Lisboa<\/div>\n
Portugal<\/div>\n<\/td>\n
\n
Tel: +351 217 946 400<\/div>\n
Fax: +351 217 946 470<\/div>\n<\/td>\n<\/tr>\n
<\/td>\n\n
NMR Equipment<\/h5>\n
    \n
  • Bruker – Biospin Fourier 300 MHz<\/li>\n<\/ul>\n<\/td>\n
\n
Unit Homepage<\/h5>\n

ULisboa – FF<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

Main Research Topics<\/h4>\n

The NMR equipment plays a key role in all chemistry-based research topics developed at the Research Institute for Medicines (iMed.ULisboa). The NMR techniques (1<\/sup>H, 13<\/sup>C, and 2D-NMR experiments) are routinely used for structure elucidation of small molecules obtained either from synthesis or natural sources, kinetic studies to elucidate reaction mechanisms, metabolic studies, including metabolite identification, and for quantification in drug development studies.<\/p>\n

 <\/p>\n

Selected Publications<\/strong><\/h4>\n
    \n
  1. Pereira JG, Ant\u00f3nio JPM, Mendon\u00e7a R, Gomes RFA, Afonso CAM. Rediscovering aminal chemistry: copper(II) catalysed formation under mild conditions. Green Chem., 2020, 22, 7484\u20137490. https:\/\/doi:10.1039\/d0gc01977a<\/a><\/li>\n
  2. Silva MJSA, Faustino H, Coelho J, Pinto MV, Fernandes A, Compa\u00f1\u00f3n I, Corzana F, Gasser G, Gois PMP. Efficient amino sulfhydryl stapling on peptides and proteins using bifunctional NHS activated acrylamides. Angew. Chem. Int. Ed. 2021; 60: 10850. https:\/\/doi:10.1002\/anie.202016936<\/a><\/li>\n
  3. Gomes-Alves AG, Duarte M, Cruz T, Castro H, Lopes F, Moreira R, Ressurrei\u00e7\u00e3o AS, Tom\u00e1s AM. Quinolin-(1H)-imines as a new chemotype against leishmaniasis: biological evaluation and mechanistic studies. Antimicrob Agents Chemother 2021; Apr 26:AAC.01513-20. DOI: 10.1128\/AAC.01513-20.<\/li>\n
  4. Barcherini V, Almeida J, Lopes E, Wang M, Silva DM, Mori M, Wang S, Saraiva L, Santos MM. Potency and Selectivity Optimization of Tryptophanol-Derived Oxazoloisoindolinones: Novel p53 Activators in Human Colorectal Cancer. ChemMedChem 2021, 16, 250\u2013258. https:\/\/doi.org\/10.1002\/cmdc.202000522<\/a><\/li>\n
  5. Ferreira RJ, Spengler G, Orthaber A, dos Santos DJVA, Ferreira, MJU. Pedrolane, a Polycyclic Diterpene Scaffold Containing a Bicyclo[2.2.1]heptane System, from Euphorbia pedroi. Org Lett 2021; 23: 274\u2013278. https:\/\/Doi:10.1021\/acs.orglett.0c03647<\/a><\/li>\n<\/ol>\n

     <\/p>\n","protected":false},"excerpt":{"rendered":"

      Faculdade de Farm\u00e1cia Universidade de Lisboa Avenida Professor Gama Pinto 1649-003 Lisboa Portugal Tel: +351 217 946 400 Fax: +351 217 946 470 NMR Equipment Bruker – Biospin Fourier 300 MHz Unit Homepage ULisboa – FF   Main Research Topics The NMR equipment plays a key role in all chemistry-based research topics developed at… Read More »Universidade de Lisboa – FF<\/span><\/a><\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":100,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":""},"_links":{"self":[{"href":"https:\/\/ptnmr.web.ua.pt\/index.php\/wp-json\/wp\/v2\/pages\/2305"}],"collection":[{"href":"https:\/\/ptnmr.web.ua.pt\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ptnmr.web.ua.pt\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ptnmr.web.ua.pt\/index.php\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/ptnmr.web.ua.pt\/index.php\/wp-json\/wp\/v2\/comments?post=2305"}],"version-history":[{"count":4,"href":"https:\/\/ptnmr.web.ua.pt\/index.php\/wp-json\/wp\/v2\/pages\/2305\/revisions"}],"predecessor-version":[{"id":3136,"href":"https:\/\/ptnmr.web.ua.pt\/index.php\/wp-json\/wp\/v2\/pages\/2305\/revisions\/3136"}],"wp:attachment":[{"href":"https:\/\/ptnmr.web.ua.pt\/index.php\/wp-json\/wp\/v2\/media?parent=2305"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}