Universidade do Minho - CQ


Departamento de Química
Universidade do Minho
Campus de Gualtar
4710-057 Braga
Tel: + 351 253 604 378
Fax: + 351 253 678 983

NMR Equipment
  • Bruker Avance 400
Unit Homepage


Main Research Topics

Structural characterization of different compounds (heterocyclic compounds with biological activity and for materials, amino acids and peptides with biological activity and as sensors and probes, functionalized Carbon-Based Materials) using 1D and 2D NMR techniques including homonuclear 1H-1H and heteronuclear correlations 1H-13C and 1H-15N. Characterization of quadrupolar metallic (27Al, 71Ga) complexes with relevance for diagnostic using medical imaging.

Selected Publications

Publications ISI 2010

  1. L. Assunção, E. Marinho, F. Proença, “Guanidine: studies on the reaction with ethyl N-(2-amino-1,2-dicyanovinyl)formimidate” Arkivoc, 2010 (v), 82-91.

  1. M. C. Paiva,W. Xu, M. F. Proença, R. Novais, E. Lægsgaard, F. Besenbacher, "Unzipping of functionalized multiwall carbon nanotubes induced by STM" Nano Letters, 2010, 10, 1764-1768.

  1. M. F. Proença, M. Costa “One-pot approach to the synthesis of novel 12H-chromeno[2´,3´:4,5]imidazo[1,2-a] pyridines in aqueous media” Tetrahedron 2010, 66, 4542-4550.

  1. E. Marinho, R. Araújo, F. Proença “The reaction of anthranilonitrile and triethylorthoformate revisited: formation of dimeric and trimeric species”, Tetrahedron 2010, 66(45), 8681-8689.

  1. A.M. Dias, I. M. Cabral, A.S. Vila-Chã, D. Cunha, N. Senhorães, S. Nobre, C. Sousa, M.F. Proença, “A facile one-pot synthesis of 3-imidazolyl 1,2,4-triazoles and 1,2,4-oxadiazolones, Synlett, 2010, 2792-2796.

  1. H. Bacelar, M.A. Carvalho, M. F. Proença,“Synthesis and in Vitro Evaluation of Substituted Pyrimido[5,4-d]pyrimidines as a Novel Class of Antimycobacterium tuberculosis agents” Eur. J. Med. Chem. 2010, 45, 3234-3239.

  1. F. Areias, J. Brea, E. Gregori-Puigjané, M.E.A. Zaki, M.A. Carvalho, Eduardo Domínguez, H. Gutiérrez-de-Terán, M. Fernanda Proença, M.I. Loza, J. Mestres, “In silico directed chemical probing of the adenosine receptor family” Bioorg. Med Chem. 2010, 18, 3043-3052.

  1. M.M. Oliveira, L.Carvalho, F. Peixoto, A.M. Oliveira-Campos, A. Reis, P. Domingues, M. Domingues, “Cleavages of photochromic compounds derived from heterocycles under Electrospray Tandem Mass Spectrometry: Study of the influence of the heteroatom in fragmentation mechanisms” Rapid Communications in Mass Spectrometry 2010, 24(14), 2171-2174.

  1. M.J. Alves, V.C.M. Duarte, H. Faustino, A. Gil Fortes “Diastereo-controled Diels-Alder Cycloadditions of Erythrose Benzylidene-Acetal 1,3-Butadienes by 4-Substituted-1,2,4-triazoline-3,5-dione. Evidence for the Stereoelectronic Effects on the Dienes” Tetrahedron: Asymmetry 2010,21, 1817-1820.

  1. R. C. Calhelha, M.-J.R.P. Queiroz “Synthesis of new thieno[3,2-b]pyridine derivatives by palladium-catalyzed couplings and intramolecular cyclizations” Tetrahedron Lett. 2010, 51, 281-283.

  1. M.-J.R.P. Queiroz, R. C. Calhelha, L.A. Vale-Silva, E. Pinto, R.T. Lima, M.H. Vasconcelos “Efficient synthesis of 6-(hetero)arylthieno[3,2-b]pyridines by Suzuki-Miyaura coupling. Evaluation of growth inhibition in human tumor cell lines, SARs and effects on the cell cycle” Eur. J. Med. Chem. 2010, 45, 5628-5634.

  1. M.-J.R.P. Queiroz, R. C. Calhelha, L.A. Vale-Silva, E.Pinto, M.S.-J. Nascimento “Novel 6-[(hetero)arylamino]thieno[3,2-b]pyridines: Synthesis and antitumoral activities” Eur. J. Med. Chem. 2010, 45, 5732-5738.

  1. M. M. M. Raposo, B. García-Acosta, T. Ábalos, R. Martínez-Manez, J. V. Ros-Lis, J. Soto, "Synthesis and study of the use of heterocyclic thiosemicarbazones as signalling scaffolding for the recognition of anions" J. Org. Chem. 2010, 75(9), 2922–2933.

  1. M.C. Paiva, F. Simon, R. Novais, T. Ferreira, M.F. Proença, W. Xu, F. Besenbacher, “Controlled functionalization of carbon nanotubes by a solvent free multicomponent approach” ACS Nano 2010, 4(12), 7379-7386.

  1. M. C. Paiva, R. M. Novais, R. F. Araújo, K. K. Pederson, M. F. Proença, C.J.R. Silva, C. M. Costa and S. Lanceros-Méndez“Organic functionalization of carbon nanofibres for composite applications” Polymer Composites 2010, 31, 3, 369-376.

  1. A.M. Salaheldin, A.M. F. Oliveira-Campos, P.Parpot, L.M. Rodrigues, M.M. Oliveira, F.P. Feixoto, “Synthesis of New Tacrine Analogues from 4-Amino-1H-pyrrole-3-carbonitrile” Helv. Chim. Acta 2010, 93, 242-248.

  1. Ana M.F. Oliveira-Campos, Joana M.O. Ribeiro, Lígia M. Rodrigues, Pier Parpot and Paulo E. Lopes, “3–{1–[(4–Methylphenyl)sulfonil]-1,4–dihydropyridin–4–yl}–1H– indole”Acta Cryst. 2010, E66, o915.

  1. A.M.F. Oliveira-Campos, L.M. Rodrigues, A.P. Esteves, M.E. Silva, A. Sivasubramanian, R. Hrdina, G.M.B. Soares, T.A.D. Pinto, O. Machalicky, “Naphthotriazole derivatives: synthesis and fluorescence properties”, Dyes and Pigments 2010, 87, 188-193.

  1. G. Pereira, E.M.S. Castanheira, P.M.T. Ferreira, M.-J.R.P. Queiroz “Synthesis and photophysical studies of new indole derivatives obtained from beta-bromo dehydroamino acids. Interaction with fluoride anion” Eur. J. Org. Chem. 2010, 464-475.

  1. C. Herbivo, A. Comel, G. Kirsch, A. Maurício, C. Fonseca, M. Belsley and M. M. M. Raposo, "Synthesis and characterization of novel efficient and thermally stable 2-aryl-5-dicyanovinylthiophenes and 5-aryl-5´-dicyanovinyl-2,2´-bithiophenes as potentially promising nonlinear optical (NLO) materials" Dyes Pigments 2010, 82(3), 217-226.

  1. J. Pina, J. S. Seixas de Melo, R.M.F. Batista, S.P.G. Costa, M.M.M. Raposo, "Synthesis and characterization of the ground and excited states of tripodal-like oligothienyl-imidazoles" J. Phys. Chem. B 2010, 114(15), 4964-4972.

  1. A. F. Fonseca, M. Belsley, E. M. Gomes, M. C. R. Castro, M. M. M. Raposo, "Molybdenum complexes bearing (bi)thienyl- or arylthienyl-substituted p-conjugated spacers: synthesis, electrochemical, spectroscopic and nonlinear optical properties", Eur. J. Inorg. Chem.2010, 19, 2998-3004.

  1. C.I.C. Esteves, M. M. M. Raposo, S. P. G. Costa, "Synthesis and evaluation of new benzathiazolyl and benzimidazolyl asparagines as amino acids based selective fluorimetric chemosensors for Cu2+",Tetrahedron 2010, 66(38), 7479-7486.

  1. L.S. Monteiro, J. Kołomańska, A.C. Suarez“Synthesis of novel non-proteinogenic amino acids: N-ethyl-a,b-dehydroamino acid methyl esters” Eur. J. Org. Chem. 2010, 6731-6735.

  1. P.M.T. Ferreira, E.M.S. Castanheira, L.S. Monteiro, G. Pereira, H. Vilaça“A mild high yielding synthesis of oxazole-4-carboxylate derivatives” Tetrahedron,2010, 66, 8672-8680.

  1. P.M.T. Ferreira, L.S. Monteiro, G. Pereira,“Synthesis and electrochemical behaviour of b-halodehydroamino acid derivatives”Amino Acids, 2010,37, 499-513.

  1. A.M.S. Soares, S.P.G. Costa, M.S.T. Gonçalves,“2-Oxo-2H-benzo[h]benzopyran as a new light sensitive protecting group for neurotransmitter amino acids” Amino Acids, 2010, 39, 121-133.

  1. A.S.C. Fonseca, M.S.T. Gonçalves, S.P.G. Costa, “Light-induced cleavage of phenylalanine model conjugates based on coumarins and quinolones” Amino Acids, 2010, 39, 699-712.

  1. A.M.S. Soares, S.P.G. Costa, M.S.T. Gonçalves,“Oxazole light triggered protecting groups: synthesis and photolysis of fused heteroaromatic conjugates”, Tetrahedron,2010, 66, 8189-8195.

  1. G. Hungerford, L. Ryderfors, M.J.G. Fernandes, M.S.T. Gonçalves, S.P.G. Costa, “One- and two-photon time-resolved fluorescence study of neurotransmitter amino acid – 5,6-benzocoumarin conjugates”, J. Photochem. Photobiol. A: Chemistry, 2010, 215, 214–222.

  1. A. de Sá, Á.A. Matias, M.I.M. Prata, C.F.G.C. Geraldes, P.M.T. Ferreira, J.P. André, "Gallium labeled NOTA-based conjugates for peptide receptor-mediated medical imaging" Bioorg. Med. Chem. Lett. 2010, 7345-7348.

  1. C. Gonçalves, M.F.M. Ferreira, A.C. Santos, M.I.M. Prata, C.F.G.C. Geraldes, J.A. Martins, F.M. Gama, “Studies on the biodistribution of dextrin nanoparticles” Nanotechnology, 2010, 21(29), article number: 295103.

  1. A. de Sá, M.I.M. Prata, C.F.G.C. Geraldes, J.P. André, "Triaza-based amphiphilic chelators: synthetic route, in vitro characterization and in vivo studies of their Ga(III) and Al(III) chelates", Journal of Inorganic Biochemistry, 2010, 104, 1051-1062.

Publications ISI 2011

  1. L.S. Monteiro, J.J. Andrade, A.C. Suárez “Synthesis of new N-ethyl dehydroamino acid derivatives: N-ethyl b,b-dibromo, N-ethyl b-bromo b-substituted, N-ethyl b,b-disubstituted N-protected dehydroamino acid methyl esters” Eur. J. Org. Chem., 2011, 6764-6772. http://dx.doi.org/10.1002/ejoc.201100907

  1. P.M.T. Ferreira, L.S. Monteiro, E.M.S. Castanheira, G. Pereira, C. Lopes, H. Vilaça “Electrochemical reduction of dehydroamino acids: Synthesis and photophysical properties of beta,beta-diarylalanines”Tetrahedron, 2011, 67, 193-200. http://dx.doi.org/10.1016/j.tet.2010.10.087

  1. S. Naik, C.M.A. Alves, P.J.G. Coutinho, M.S.T. Gonçalves, “N-(Di)icosyl-substituted benzo[a]phenoxazinium chlorides: synthesis and evaluation as near-infrared membrane probes”, Eur. J. Org. Chem. 2011, 2491-2497.http://dx.doi.org/10.1002/ejoc.201001579.

  1. C.M.A. Alves, S. Naik, P.J.G. Coutinho, M.S.T. Gonçalves, “Novel DNA fluorescence probes based on N-[5-(11-functionalised-undecylamino)-9H-benzo[a]phenoxazin-9-ylidene]propan-1-aminium chlorides: synthesis and photophysical studies”, Tetrahedron Letters 2011, 52, 112–116. http://dx.doi.org/10.1016/j.bbr.2011.03.031

  1. M.J.G. Fernandes, S.P.G. Costa, M.S.T. Gonçalves, “Phototriggering of neuroactive amino acids from 5,6-benzocoumarinyl conjugates”, Tetrahedron2011, 67, 2422-2426. http://dx.doi.org/10.1016/j.tet.2011.01.090

  1. A.M. Piloto, A.M.S. Soares, G. Hungerford, S.P.G. Costa, M.S.T. Gonçalves, “Long-wavelength photolysis of amino acid 6-(methoxy-2-oxo-2H-naphtho[1,2-b]pyran-4-yl)methyl esters”, Eur. J. Org. Chem. 2011, 5447-5451. http://dx.doi.org/10.1002/ejoc.201100391

  1. A.M. Piloto, A.M.S. Soares, S.P.G. Costa, M.S.T. Gonçalves, “Photorelease of amino acids from novel thioxobenzo[f]benzopyran ester conjugates”, Amino Acids, 2011. http://dx.doi.org/10.1007/s00726-011-0969-0

  1. M.-J.R.P. Queiroz, R. C. Calhelha, L.A. Vale-Silva, E. Pinto, G.M. Almeida, M. Helena Vasconcelos “Synthesis and Evaluation of Tumor Cell Growth Inhibition of Methyl 3-Amino-6-[(hetero)arylethynyl]thieno[3,2-b]pyridine-2-carboxylates. Structure-Activity Relationships, Effects on the Cell Cycle and Apoptosis Eur. J. Med. Chem. 2011, 46, 236-240. http://dx.doi.org/10.1016/j.ejmech.2010.11.009

  1. A. Begouin, M.-J.R.P. Queiroz “Tandem Pd/C-CuI catalyzed Sonogashira coupling and intramolecular cyclization from 2-bromonicotinic acid and arylacetylenes to 4-azaphthalides and 5-azaisocoumarins” Helvetica Chimica Acta,2011, 94, 1792-1801. http://dx.doi.org/10.1002/hlca.201100060

  1. B. F. Hermenegildo, G. Pereira, A.S. Abreu, E.M.S. Castanheira, P.M.T. Ferreira, M.-J. R.P. Queiroz “Phenanthrenyl-indole as a fluorescent probe for peptides and lipid membranes” J. Photochem. Photobiol. A: Chemistry, 2011,221, 47-57. http://dx.doi.org/10.1016/j.jphotochem.2011.04.022

  1. A.M. Dias, A.S. Vila-Chã, A.L. Costa, D.P. Cunha, N. Senhorães, M.F.Proença, “Versatile Synthesis of 5-Aminoimidazole-4-carboxylic Acid Derivatives” Synlett 2011, 2675-2680. http://dx.doi.org/10.1055/s-0031-1289528

  1. M.M.M. Raposo, M.C.R. Castro, A. Maurício C. Fonseca, M. Fátima S. Cardoso, M. Belsley, L. M. Carvalho, P.J. Coelho, “Synthesis and characterization of novel diazenes bearing pyrrole, thiophene and thiazole heterocycles as efficient photochromic and nonlinear optical (NLO) materials”, Dyes Pigments, 2011, 91(1), 62-73. http://dx.doi.org/10.1016/j.dyepig.2011.02.012

  1. M.M.M. Raposo, M.C.R. Castro, P. Schellenberg, A. Maurício C. Fonseca, M. Belsley, “Design, synthesis and characterization of electrochemical, nonlinear optical (NLO) properties and theoretical studies of novel thienylpyrrole azo dyes bearing benzothiazole acceptor groups”, Tetrahedron 2011, 67(29), 5189-5198. http://dx.doi.org/10.1016/j.tet.2011.05.053

  1. M.M.M. Raposo, M.C.R. Castro, M. Belsley, A.M.C. Fonseca, “Push-pull bithiophene azo-chromophores bearing thiazole and benzothiazole acceptor moieties: synthesis and evaluation of their redox and nonlinear optical properties”, Dyes Pigments, 2011, 91(3), 454-465. http://dx.doi.org/10.1016/j.dyepig.2011.05.007

  1. A. Fontes, M. Isabel M. Prata, C.F.G.C. Geraldes, J.P. André, “Ga(III) chelates of amphiphilic DOTA-based ligands: synthetic route and in vitro and in vivo studies” Nuclear Medicine and Biology 2011, 38363–370. http://dx.doi.org/10.1016/j.nucmedbio.2010.10.003

  1. C.I.C. Esteves, M.M.M. Raposo, S.P.G. Costa, "Novel highly emissive non proteinogenic amino acids: synthesis of 1,3,4-thiadiazolyl asparagines and evaluation as fluorimetricchemosensors for biologically relevant transition metal cations”, Amino Acids 2011, 40, 1065-1075. http://dx.doi.org/10.1007/s00726-010-0730-0

  1. R.M.F. Batista, E. Oliveira, S.P.G. Costa, C. Lodeiro, M.M.M. Raposo,"Imidazo-benzo-15-crown-5 ether bearing arylthienyl and bithienyl moieties as novel fluorescent chemosensors for Pd2+ and Cu2+",Tetrahedron 2011, 67(37) 7106-7113. http://dx.doi.org/10.1016/j.tet.2011.06.106

  1. E. Oliveira, D Genovese, R. Juris, N. Zaccheroni, J.L. Capelo, M.M.M. Raposo, S.P.G. Costa, L. Prodi, C. Lodeiro, “Synthesis of new emissive peptides probes based on benzo[d]oxazol derivatives and their gold and sílica nanoparticles”, Inorg. Chem.,2011, 50(18), 8834–8849. http://dx.doi.org/10.1021/ic200792t

  1. R.M.F. Batista, E. Oliveira, S.P.G. Costa, C. Lodeiro, M.M.M. Raposo,"(Oligo)thienyl-imidazo-crown ether derivatives: synthesis, photophysical studies and evaluation of their chemosensory properties", Talanta, 2011,85(5), 2470-2478. http://dx.doi.org/10.1016/j.talanta.2011.07.107

  1. M.J. Alves, F.T. Costa, Vera C.M. Duarte, A. Gil Fortes, J.A. Martins, N.M. Micaelo, “Advances in the synthesis of homochiral (−)-1-azafagomine and (+)-5-epi-1-azafagomine. 1-N-phenyl carboxamide derivatives of both enantiomers of 1-azafagomine: leads for the synthesis of active α-glycosidase inhibitors”, J. Org. Chem. 2011, 76(23) 9584-9592. http://dx.doi.org/10.1021/jo201486q

  1. N. Senhorães, A.M. Dias, L.M. Conde, M.F. Proença,“One-Pot Regioselective Synthesis of 2,6,9-Trisubstituted Adenines” Synlett 2011 181-186. http://dx.doi.org/10.1055/s-0030-1259289

  1. M. Zaki, M.F. Proença, “Synthesis of 6-cyano and 6-unsubstituted 2-aryl-8-oxopurine from a common 2-oxoimidazole precursor” Tetrahedron 2011, 67(4), 755-762. http://dx.doi.org/10.1016/j.tet.2010.11.064

  1. M. Costa, M.F. Proença, “A one-pot synthesis of substituted pyrido[2,3-b]indolizines” Tetrahedron,2011, 67(6), 1071-1075. http://dx.doi.org/10.1016/j.tet.2010.12.047

  1. M. Costa, F. Proença,”2-Aryl-1,9-dihydrochromeno[3,2-d]imidazoles: a facile synthesis from salicylaldehydes and arylideneaminoacetonitriles” Tetrahedron 2011, 67(10), 1799-1804. http://dx.doi.org/10.1016/j.tet.2011.01.035

  1. M. Costa, F. Areias, M. Castro, J. Brea, M.I. Loza, F. Proença, “Synthesis of novel chromene scaffolds for adenosine receptors” Organic & Biomolecular Chem. 2011, 9, 4242-4249. http://dx.doi.org/10.1039/c1ob05305a

  1. M. Costa, F. Proença, “Selective synthesis of some imidazopyridine-fused chromones” Tetrahedron,2011, 67, 8622 – 8627. http://dx.doi.org/10.1016/j.tet.2011.09.054

Publications ISI 2012

  1. R. C. Calhelha, I. C. F. R. Ferreira, D. Peixoto, R M. V. Abreu, L. A. Vale-Silva, E. Pinto, R. T. Lima, M. I. Alvelos, M. H. Vasconcelos, M.-J. R. P. Queiroz “Aminodi(hetero)arylamines in the Thieno[3,2-b]pyridine Series: Synthesis, Effects in Human Tumor Cells Growth, Cell Cycle Analysis, Apoptosis and Evaluation of Toxicity Using Non-Tumor Cells” Molecules 2012, 17(4), 3834-3843. (IF2011= 2.386). http://dx.doi.org/10.3390/molecules17043834

  1. M.-J. R. P. Queiroz, S. Dias, D. Peixoto, A. R. O. Rodrigues, A. D. S. Oliveira, P. J.G. Coutinho, L. A. Vale-Silva, E. Pinto, E. M. S. Castanheira “New potential antitumoral di(hetero)arylether derivatives in the thieno[3,2-b]pyridine series: synthesis and fluorescence studies in solution and in nanoliposomes” J. Photochem. Photobiol. A - Chem. 2012, 238, 71-80. (IF 2.421). http://dx.doi.org/10.1016/j.jphotochem.2012.04.007

  1. D. Peixoto, A. Begouin, M.-J.R.P. Queiroz "Synthesis of 2-(hetero)arylthieno[2,3-b] or [3,2-b]pyridines from 2,3-dihalopyridines, (hetero)arylalkynes and Na2S. Further functionalizations” Tetrahedron 2012, 68, 7082-7094. (IF2011 = 3.025) http://dx.doi.org/10.1016/j.tet.2012.06.057

  1. D.A.L. Salgueiro; V.C.M. Duarte; C.E.A. Sousa; M.J. Alves; A. Gil Fortes,“Diastereo-selectivity in Diels–Alder Cycloadditions of Erythrose Benzylidene-acetal 1,3-Butadienes with Maleimides”, Synlett, 23, 1765-1768, 2012. (IF= 2.71). http://dx.doi.org/10.1055/s-0031-1289785

  1. E. Genin,V. Hugues, G. Clermont, C. Herbivo, M.C.R. Castro, A. Comel, M.M.M. Raposo, M. Blanchard-Desce "Fluorescence and two-photon absorption of push-pull aryl(bi)thiophenes: structure-property relationships", Photochem. Photobiol. Sci., 2012, 11(11) 1756-1766. (IF2011: 2.584). http://dx.doi.org/10.1039/c2pp25258a

  1. C. Correia, M. A. Carvalho, A. Rocha, M. F. Proença, “General Synthetic Approach to 2-Phenolic Adenine Derivatives”,Synlett 2012, 1923-1926 (IF=2.062) http://dx.doi.org/10.1055/s-0031-1290694

  1. D. A. L. Salgueiro, C. E. A. Sousa, A. Gil Fortes, M. J. Alves, “Diels-Alder Cycloaddition in the Synthesis of 1-Azafagomine, Analogues, and Derivatives as Glycosidase Inhibitors”, Mini Reviews in Med. Chem., 12, 1465-1476, 2012. (IF 2.53). http://dx.doi.org/10.2174/138955712803832663

  1. M. Costa, F. Areias, M. Castro, J. Brea, J. Mestres, F. Proença, M. Loza, “A new chromene scaffold for adenosine A2A receptors. Synthesis, pharmacology, and structure-activity relationships” Eur.J. Med. Chem., 2012, 54, 303-310 (IF 3.346) http://dx.doi.org/10.1016/j.ejmech.2012.05.009

  1. T. A. Dias,M. F. Proença, An ecofriendly approach to the synthesis of the 3-phenylsulfonyl-2H-chromenescaffold” Tetrahedron Letters, 2012, 53 (39), 5235-5237. (IF2.683). http://dx.doi.org/10.1016/j.tetlet.2012.07.069

  1. A. Sivasubramanian, K.K.G. Narasimha, R. Rathnasamy. A. M.F. Oliveira Campos, “A new antifeedant clerodane diterpenoid from Tinospora cordifolia”, Natural Product Research, 2012, 1–6, (IF1.009). http://dx.doi.org/10.1080/14786419.2012.722088

  1. B. Pedras, R.M.F. Batista, L. Tormo, S.P.G. Costa, M.M.M. Raposo, G. Orellana, J.L. Capelo, C. Lodeiro, "New Ru(II) Thienyl-imidazo-phenanthroline polypyridyl complexes: synthesis, characterization, photophysical studies and interaction with DNA", Inorg. Chim. Acta, 2012, 381, 95-103. (IF2011: 1.846). http://dx.doi.org/10.1016/j.ica.2011.07.020

  1. L.E. Santos-Figueroa, M.E. Moragues, M.M.M. Raposo, R.M.F. Batista, R. C.M. Ferreira, S.P.G. Costa, F. Sancenón, R. Martínez-Máñez, J.V. Ros-Lis, J. Soto,“Synthesis and evaluation of fluorimetric and colorimetric chemosensors for anions based on (oligo)thienyl-thiosemicarbazones” Tetrahedron 2012, 68(35), 7179-7186. (IF2011: 3.025). http://dx.doi.org/10.1016/j.tet.2012.06.021

  1. R.M.F. Batista, R.C.M. Ferreira, M.M.M. Raposo,S.P.G. Costa, "Novel optical chemosensors for anion and cations based on an amino acid core functionalised with benzimidazoles", Tetrahedron, 2012, 68(36), 7322-7330. (IF2011: 3.025). http://dx.doi.org/10.1016/j.tet.2012.06.087

  1. L.E. Santos-Figueroa, M.E. Moragues, M.M.M. Raposo, R.M.F. Batista, R. C.M. Ferreira, S. P. G. Costa, F. Sancenón, R. Martínez-Máñez, J.V. Ros-Lis, J. Soto, “Synthesis and evaluation of thiosemicarbazones functionalized with furyl moieties as new chemosensors for anion recognition”, Org Biomol Chem; 2012, 10(36), 7418-7428. (IF2011: 3.696). http://dx.doi.org/10.1039/c2ob26200b

  1. T.A.D. Pinto, R. Hrdina, G. Kirsch, A.M.F. Oliveira-Campos, L.M. Rodrigues, A.P. Esteves, “Synthesis of esters derived from 2,3,4-tri-O-benzyl-alpha-D-methylglucoside”, ARKIVOC, 2012, Part 6, 185-193.(IF2011: 1.252)

  1. M.S.T. Gonçalves, A.M.F. Oliveira-Campos, L.M. Rodrigues, M.F.R.P. Proença, “Synthesis of 4-amino-3,5-dicyano-arylpyrazoles. Part 2: isolation and characterization of byproducts”, Synth. Commun., 2012, 42 (11), 1695-1703. (IF 1.062) http://dx.doi.org/10.1080/00397911.2010.543304

  1. C. S. Francisco, L. R. of novel benzofurocoumarin analogues and their anti-proliferative effect on human cancer cell lines”, Eur. J. Med. Chem., 2012, 47, 370-376. (IF 3.346). http://dx.doi.org/10.1016/j.ejmech.2011.11.005

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